Sophia M. Vrba

The paper investigates how neuroinflammation affects the ethmoid bone marrow region and its role in immune responses using scRNAseq and flow cytometry in a mouse model.

This study shows that amyloid-beta accumulates in the spinal cord of AD mice and is linked to lower urinary tract dysfunction through altered neuronal signaling.

The paper characterizes myeloid cell populations at the cribriform plate during EAE-induced neuroinflammation, finding they exhibit tolerance and reduced inflammatory profiles.

This study shows that in 24-month-old APP/PS1 mice, cribriform plate lymphatics have reduced CSF efflux and A{beta} accumulation, along with inflammation and lymphatic atrophy.