Yazmín Ramiro Cortés

The paper investigates synaptic competition during long-term depression in Fragile X Syndrome, finding that FXS mutant neurons lack competition, allowing all stimulated spines to shrink.

SpineS is an open-source software for automatic longitudinal analysis of dendritic spine dynamics with manual intervention, showing high performance on two-photon and confocal imaging datasets.

This study investigates how homeostatic plasticity affects dendritic spine volumes and modifies Hebbian plasticity thresholds and specificity in mouse hippocampal neurons.