Author

Laurens Wachsmuth

University of CologneORCID 0000-0003-1701-9384Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Alfredo Cabrera‐OreficeiD· 1 shared Ana J. García Sáez· 1 shared Asma MajouliD· 1 shared Christina KunziD· 1 shared Eleonora Germana MargheritisiD· 1 shared Gerhard HummeriD· 1 shared Katia CosentinoiD· 1 shared KC FarrelliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alfredo Cabrera‐OreficeORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintSep 30, 2026

Structural mechanism of Gasdermin E-mediated mtDNA release from apoptotic mitochondria

Lisa Hohorst, Raed Shalaby, Nadine Gehle…·Ana J. García Sáez

This study identifies GSDME-N as a mediator of mitochondrial inner membrane permeabilization and mtDNA release during apoptosis, revealing its structural mechanism and impact on inflammatory responses.

DOI 10.64898/2026.09.29.755391

experimental assay

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