Author

Zhen Li

Sheng Jing HospitalORCID 0000-0003-1760-7741Unclaimed ORCID profile · follow to get notified of new preprints

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Zhen Li10 papers · Beijing National Research Center for Information Science and Technology

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Heng CaiiD· 1 shared Jian ZhengiD· 1 shared Jiayou Zheng· 1 shared Lu ZhuiD· 1 shared Qianshuo Liu· 1 shared Sheng WangiD· 1 shared Shuguang Robert CuiiD· 1 shared Shuo CaoiD· 1 shared

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2020-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Heng CaiORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 5, 2025

Beyond RNA Structure Alone: Complex-Aware Feature Fusion for Tertiary Structure-based RNA Design

Zixun Zhang, Jiayou Zheng, Yuzhe Zhou…·Zhen Li

The paper introduces CARD, a method that integrates complex-level information to improve tertiary structure-based RNA design by incorporating protein features and affinity evaluation.

1 citation

deep learningstatistical model

𝕏 PostBluesky

Molecular BiologyRNA BiologyPeer-reviewedMay 6, 2020

TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment

Qianshuo Liu, Lu Zhu, Xiaobai Liu…·Yixue Xue

This study identifies a TRA2A/LINC00662/ELK4 axis that regulates BBB permeability in Alzheimer's disease by affecting ELK4 mRNA stability.

33 citations

humanbulk RNA-seq

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