NeuroscienceBrain CommunicationsPeer-reviewed
Mutant HTT protein decreases with CAG repeat expansion: implications for therapeutics and bioassays.
Christian Landles, Georgina F Osborne, Jemima M Phillips…·Gillian P. Bates
The paper shows that mutant HTT levels decrease with CAG repeat expansion, suggesting therapeutic strategies should target HTT1a instead of full-length HTT.
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