Author

Konstantin Bobkov

Rancho BioSciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Christian LandlesiD· 2 shared Georgina F OsborneiD· 2 shared Gillian P. BatesiD· 2 shared Iulia M NitaiD· 2 shared Jemima M PhillipsiD· 2 shared Jonathan R. Greene· 2 shared Kirupa Sathasivam· 2 shared María Cañibano-PicoiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Christian LandlesORCID

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2 papers

Recent·Most cited

Lowering the HTT1a transcript as an effective therapy for Huntingtons disease

Aikaterini Smaragdi Papadopoulou, Julia F. Alterman, Christian Landles, Edward J. Smith, Faith Conroy, Jemima M Phillips, María Cañibano-Pico, Iulia M Nita, Georgina F Osborne, Arzo Iqbal, Sarah G. Aldous, Marie K. Bondulich, Casandra Gomez-Paredes, Kirupa Sathasivam, Daniel O’Reilly, , Gillian P. Bates

The paper shows that lowering HTT1a transcript levels delays molecular and neuropathological phenotypes in a Huntington's disease mouse model.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

Mutant HTT protein decreases with CAG repeat expansion: implications for therapeutics and bioassays.

Christian Landles, Georgina F Osborne, Jemima M Phillips, María Cañibano-Pico, Iulia M Nita, Nadira S. Ali, Konstantin Bobkov, Jonathan R. Greene, Kirupa Sathasivam, Gillian P. Bates

The paper shows that mutant HTT levels decrease with CAG repeat expansion, suggesting therapeutic strategies should target HTT1a instead of full-length HTT.

Brain Communications · Jan 1, 2024Peer-reviewedNeuroscience