Sarah Jarvis

The paper presents a multiscale simulator for peripheral nerve signaling that integrates biophysical axon models with extracellular space models to predict signal shapes and stimulation thresholds.

This paper develops a computational model to study how dendritic morphology affects neuronal gain modulability using optogenetic simulations and validates findings on pyramidal and stellate cells.

The paper demonstrates how dendritic non-linear processing enables stimulus selectivity in neurons, even when preferred stimulus input is not dominant, and shows increased robustness to synaptic and dendritic failures.