BiochemistryNature CommunicationsPeer-reviewed
Deciphering the evolutionary origin of the stereoselectivity of short-chain dehydrogenases in the oxidation of the monoterpenol 1-borneol
Jasmin Zuson, Carl P. O. Helmer, Bruno Di Geronimo…·Robert Kourist
The paper investigates how natural evolution creates enantioselectivity in plant borneol dehydrogenases through ancestral sequence reconstruction and simulations.
DOI 10.1038/s41467-026-76435-1