BioinformaticsbioRxivPreprint
Single-cell based integrative analysis of transcriptomics and genetics reveals robust associations and complexities for inflammatory diseases
Hope A. Townsend, Kaylee J. Rosenberger, Lauren A. Vanderlinden…·Fan Zhang
This study integrates GWAS and scRNA-seq to identify genetically relevant cell states in inflammatory diseases, finding scDRS outperforms scGWAS in capturing disease-relevant cellular heterogeneity.