Kun‐Liang Guan

This study introduces CM-SLP, a platform to identify non-oncology drugs that enhance cancer cell death under altered nutrient conditions by targeting metabolic vulnerabilities.

This study identifies two Hippo signaling modules, HPO1 and HPO2, that regulate hepatocyte and cholangiocyte maturation at distinct developmental stages and spatial contexts in mouse livers.

This study identifies IGF2 as a mediator of Hippo signaling in liver size control, showing its role in promoting liver growth and hepatoblastoma through IGF1R activation.

The paper identifies HSat3 DNA as a platform for transcription factor binding, showing it enhances nucleolar RNA Polymerase I activity through Hippo pathway interactions.