Author

Joseph E. Ippolito

Washington University in St. LouisORCID 0000-0003-1913-5573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Joseph BloomiD· 1 shared Aaron DiAntonioiD· 1 shared Ajit George· 1 shared Akash J. PateliD· 1 shared Akdes Serin HarmancıiD· 1 shared Albert H. KimiD· 1 shared Alicia Yang· 1 shared Allegra A. PettiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

A. Joseph BloomORCID

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3 papers

Recent·Most cited

Molecular BiologyJNCI Journal of the National Cancer InstitutePeer-reviewedJan 27, 2025

NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas

Bhuvic Patel, Sangami Pugazenthi, Collin William English…·Albert H. Kim

This study identifies NF2 loss-of-function and hypoxia as drivers of radiation resistance in Grade 2 meningiomas through genetic, histopathological, and transcriptional analyses.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 29, 2022

Disruption of lactate metabolism in the peripheral nervous system leads to motor-selective deficits

A. Joseph Bloom, Amber R. Hackett, Amy M. Strickland…·Jeffrey Milbrandt

This study shows that disrupting lactate metabolism in Schwann cells or motor neurons causes motor axon degeneration, while sensory axons remain unaffected, highlighting a specific dependency of motor axons on lactate shuttling.

8 citations

mouseexperimental assay

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 22, 2021

Deep neural network analysis employing diffusion basis spectrum imaging metrics as classifiers improves prostate cancer detection and grading

Zezhong Ye, Qingsong Yang, Joshua Yao-Yu Lin…·Sheng‐Kwei Song

Diffusion histology imaging noninvasively and accurately detects and grades prostate cancer.

DOI 10.1101/2021.03.22.436514

humanimaging

𝕏 PostBluesky