Rebekka Wild

This study identifies a glycosaminoglycan-degrading Polysaccharide Utilization Locus in Segatella oris and characterizes its four enzymes, including a novel Prevotellaceae endosulfatase.

This study identifies four heterodimeric complexes involved in human chondroitin sulfate chain polymerization and proposes a non-processive, disruptive mechanism based on structural and functional analyses.

The paper presents the cryo-EM structure of the human EXT1-EXT2 complex, revealing its dimeric architecture and catalytic specificity in heparan sulfate biosynthesis.