F. Galactéros

This study uses polygenic scores to show asthma genetics are linked to ACS recurrence risk, but not occurrence, and highlights the role of HbF in modulating this risk.

The paper evaluates polygenic trait scores for hematological traits in sickle cell disease patients, finding limited predictive power for complications but significant associations for fetal hemoglobin.

The paper uses Mendelian randomization to confirm a causal link between L-glutamine levels and reduced painful crises in sickle cell disease, while finding no significant causal relationships for other metabolites.