Thomas Pincez

This study shows that inhibiting macrophage NEU1 reduces platelet clearance in ITP by limiting phagocytosis, suggesting NEU1 as a therapeutic target.

This study uses polygenic scores to show asthma genetics are linked to ACS recurrence risk, but not occurrence, and highlights the role of HbF in modulating this risk.

The paper uses CRISPR screens to identify genes and non-coding regions affecting red blood cell density, finding 17 genes and 13 regions, some novel, that regulate this trait.

The paper evaluates polygenic trait scores for hematological traits in sickle cell disease patients, finding limited predictive power for complications but significant associations for fetal hemoglobin.