Author

Harding H. Luan

NGM Biopharmaceuticals (United States)ORCID 0000-0003-2044-2159Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Harding H. Luan1 paper

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Daniel J. LeeiD· 1 shared Evan M KochiD· 1 shared Joshua S. LichtmaniD· 1 shared Shamil R. SunyaeviD· 1 shared Vladimir B. SeplyarskiyiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Daniel J. LeeORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

GeneticsNature GeneticsPeer-reviewedNov 30, 2023

A mutation rate model at the basepair resolution identifies the mutagenic effect of Polymerase III transcription

Vladimir B. Seplyarskiy, Evan M Koch, Daniel J. Lee…·Shamil R. Sunyaev

The paper introduces a basepair-resolution mutation rate model, Roulette, which identifies a 10-fold increase in mutation rate for Polymerase III-transcribed genes and detects elevated rates in testis-specific transcription factor binding sites.

56 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky