Synthetic BiologyBriefings in BioinformaticsPeer-reviewed
Protein engineering via Bayesian optimization-guided evolutionary algorithm and robotic experiments
Ruyun Hu, Lihao Fu, Yongcan Chen…·Tong Si
This paper introduces BO-EVO, a Bayesian optimization-guided evolutionary algorithm that improves protein engineering efficiency by enabling batched robotic experiments and achieving significant improvements in enzyme specificity.
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