GeneticsMammalian GenomePeer-reviewed
PKM2 ablation enhanced retinal function and survival in a preclinical model of retinitis pigmentosa
Ethan Zhang, Joseph Ryu, Sarah R. Levi…·Stephen H. Tsang
This study shows that PKM2 ablation improves photoreceptor survival and function in a preclinical RP model, suggesting metabolic reprogramming as a potential treatment.
19 citations