Author

Cheng Lai Victor Huang

University of California, BerkeleyORCID 0000-0003-2163-6596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

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Christina Ho· 1 shared Jack F. Kirsch· 1 shared Maxim Shatsky· 1 shared Yu-Hsiu Tony LiniD· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperBioinformatics

Christina Ho

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintDec 19, 2017

A general method to predict the effect of single amino acid substitutions on enzyme catalytic activity

Yu-Hsiu Tony Lin, Cheng Lai Victor Huang, Christina Ho…·Jack F. Kirsch

The paper develops a machine learning method to predict which single amino acid substitutions in enzymes are likely to significantly reduce kcat/Km values, improving experimental efficiency.

1 citation

protein sequencemachine learning (classical)

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