Uduak Z. George

This study shows mutant IDH1 increases sEV secretion and alters their cargo composition in glioma and chondrosarcoma cells, with D2HG packaged into sEVs and cell-type-specific cargo remodeling.

This study quantifies coronary microvascular structure and function in mouse models of CMVD, identifying age, sex, and metabolic factors as key contributors to disease.

This study shows that applying uniaxial force during puberty changes mammary duct orientation and increases ductal network length in mice.

This study shows that IDH1 R132Q mutants produce more D2HG than R132H mutants, leading to more aggressive tumors through distinct epigenetic and transcriptomic changes.