Tatiana Dvorkina

HORmon automates human centromere annotation by integrating monomer and HOR inference, producing results consistent with prior semi-manual studies.

A gapless 3.055 billion bp human genome from HiFi and ultra-long nanopore reads resolves all centromeric arrays and acrocentric p-arms, adding 182 Mbp of new sequence.

The paper presents a comprehensive analysis of fully assembled human centromeres, revealing their architecture, variation, and evolutionary dynamics at high resolution.

This paper completes the linear assembly of human chromosome 8, resolves long-standing gaps, and analyzes the evolutionary history of its centromeric regions across great apes.

SPAligner aligns long diverged molecular sequences to assembly graphs, efficiently mapping third-generation sequencing data and aiding gene identification in metagenomics.

The paper introduces a StringDecomposer algorithm to translate long reads into centromere monomers, identifying a novel monomer that improves centromere assembly.