Sébastien Bouret

This study uses pharmacogenetic inhibition of locus coeruleus neurons in monkeys to show that LC activity is critical for cognitive effort during a memory-demanding task.

This study shows that reference point-dependent reinforcement learning, involving relative value encoding, is conserved in humans and rats despite some species-specific differences in behavioural and computational parameters.

The paper examines the evolutionary factors influencing prefrontal brain regions in primates, finding that ecological constraints have a stronger impact on their size than social constraints.

This study investigates strategic exploration in macaques, showing distinct neural circuits in ACC/MCC-dlPFC and OFC that support strategic decision-making and counterfactual learning.

This study investigates how D1-like and D2-like dopamine receptors influence cost/benefit evaluation and motivation in monkeys using pharmacological manipulation and PET imaging.

This study shows that reducing noradrenaline levels in rhesus monkeys decreases exerted force and alters decision-making related to effort.

This study compares noradrenergic and dopaminergic neuron activity in monkeys during task performance, finding that noradrenergic neurons predict re-engagement after failure and respond to task state changes.

This study investigates the role of noradrenaline in behavioural flexibility and motivation using a cost/benefit decision task and clonidine manipulation, finding distinct effects on choice volatility and force production.

This study examines the roles of the lateral prefrontal cortex and orbitofrontal cortex in abstract rule learning and reversal in monkeys, finding distinct impairments in each region.