GenomicsGenome ResearchPeer-reviewed
Discovering human transcription factor interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays
Shaleen Shrestha, Jared Allan Sewell, Clarissa Stephanie Santoso…·Juan I. Fuxman Bass
The paper develops enhanced yeast one-hybrid assays to study TF binding to repetitive elements, variants, and novel motifs, identifying 75 TFs interacting with Alu elements and changes in TF binding associated with cancer-related mutations.
12 citations