Author

Vance W. Jaeger

University of LouisvilleORCID 0000-0003-2294-4451Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonis Margaritakis· 1 shared David H. JohnsoniD· 1 shared John M. WhiteiD· 1 shared Orianna H. Kou· 1 shared Peter J. ChungiD· 1 shared Stephanie Y. Ramirez· 1 shared Wade F. ZenoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Antonis Margaritakis

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1 paper

Recent·Most cited

BiophysicsCommunications BiologyPeer-reviewedAug 7, 2025

Lipid Packing Defects are Necessary and Sufficient for Membrane Binding of alpha-Synuclein

David H. Johnson, Orianna H. Kou, John M. White…·Wade F. Zeno

This study shows that N-terminal acetylation of alpha-synuclein reduces its dependence on anionic lipids for membrane binding, demonstrating that membrane packing defects alone can drive binding.

19 citationstop 3%

humanproteomics

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