Katharina Kocher

This study identifies antigen-reactive CD4+ T cells after SARS-CoV-2 vaccination using single-cell RNA and TCR sequencing, revealing phenotypic differences between stimulated and unstimulated states.

The paper analyzes T cell responses to mRNA vaccination, finding that polyclonality and high, but not maximum, antigen receptor avidity correlate with response quality.

The paper benchmarks T-cell receptor-epitope predictors using ePytope-TCR, showing performance on datasets and highlighting biases in prediction scores across epitope classes.