Author

Bernd M. Spriewald

Friedrich-Alexander-Universität Erlangen-Nürnberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Kilian SchoberiD· 3 shared Benjamin SchubertiD· 2 shared Christine Schülein· 2 shared Felix DrostiD· 2 shared Katharina KocheriD· 2 shared Myriam GrotziD· 2 shared Abel Mekonnen TesfayeiD· 1 shared Arif Bülent EkiciiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Kilian SchoberORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity

Nikolaj Pagh Kristensen, Thanos Tsaktanis, Sina Frischholz, Jasim Kada Benotmane, Lucia Klotz, Philipp Hilgendorf, M. Grotz, Mariana Sousa, Lasse Frank Voss, Stefan Schattgen, Vanessa Lang, Hannah Reimann, Cosima Storr, Roland Lang, Bernd M. Spriewald, , Kilian Schober

The paper identifies an EBV-specific T cell program in MS patients that contributes to CNS autoimmunity through B cell and myeloid cell activation.

bioRxiv · Oct 1, 2026 · PreprintImmunology

Antigen-reactive CD4+ T cells after SARS-CoV-2 vaccination show divergent phenotypic states with or without restimulation bias

Katharina Kocher, Felix Drost, Christine Schülein, Bernd M. Spriewald, Benjamin Schubert, Kilian Schober

This study identifies antigen-reactive CD4+ T cells after SARS-CoV-2 vaccination using single-cell RNA and TCR sequencing, revealing phenotypic differences between stimulated and unstimulated states.

iScience · Jun 1, 2026Peer-reviewedImmunology

Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity

Katharina Kocher, Felix Drost, Abel Mekonnen Tesfaye, Carolin Moosmann, Christine Schülein, Myriam Grotz, Elvira D’Ippolito, Frederik Graw, Bernd M. Spriewald, Dirk Hans Busch, Christian Bogdan, Matthias Tenbusch, Benjamin Schubert, Kilian Schober

The paper analyzes T cell responses to mRNA vaccination, finding that polyclonality and high, but not maximum, antigen receptor avidity correlate with response quality.

Science Immunology · Oct 3, 2025Peer-reviewedImmunology

IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression

David Falck, Maria V Sokolova, Carolien A. M. Koeleman, Vanessa Irumva, Philipp Kirchner, Sebastian R. Schulz, Katja G. Schmidt, Thomas Harrer, Arif Bülent Ekici, Bernd M. Spriewald, Georg Andreas Schett, Manfred Wuhrer, Martin Herrmann i, Ulrike Steffen

The paper compares glycosylation patterns of IgA1 and IgA2, finding subclass-specific differences despite similar glycosylation enzyme expression.

Cell Communication and Signaling · Feb 17, 2025Peer-reviewedImmunology