Author

Filipe Ferreira dos Santos

Universidade de São PauloORCID 0000-0003-2335-463XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Approach:mixed model· 1 Organism:mouse· 1

Frequent Co-Authors

Pedro A. F. GalanteiD· 4 shared Felipe R. C. dos SantosiD· 2 shared Gabriela D. A. GuardiaiD· 2 shared Rafael L. V. MercuriiD· 2 shared Alexander BirbrairiD· 1 shared Aline Rangel PozzoiD· 1 shared Anacleto Silva de SouzaiD· 1 shared Antonis RokasiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBioinformatics

Pedro A. F. GalanteORCID

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Author profile →

4 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 28, 2026

Processed pseudogenes as dynamic substrates of vertebrate genome evolution

Rafael L. V. Mercuri, Gabriela D. A. Guardia, Daniela Moreira Mombach…·Pedro A. F. Galante

The paper shows processed pseudogenes are dynamic evolutionary elements, not inert, and links their abundance to life-history traits and cancer-related dynamics across vertebrates.

DOI 10.64898/2026.06.26.734816

humanmouse

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BioinformaticsbioRxivPreprintApr 22, 2024

FREDDIE: A comprehensive tool for detecting exonization of retrotransposable elements in short and long RNA sequencing data

Rafael L. V. Mercuri, Thiago L. A. Miller, Filipe Ferreira dos Santos…·Pedro A. F. Galante

FREDDIE detects exonization of retrotransposable elements in RNA-seq data, identifying chimeric transcripts in cancer cell lines and glioblastoma samples.

3 citations

humanbulk RNA-seq

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Molecular BiologyACS OmegaPeer-reviewedAug 25, 2022

Molecular dynamics analysis of fast-spreading severe acute respiratory syndrome coronavirus 2 variants and their effects in the interaction with human angiotensin-converting enzyme 2

Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Gabriela D. A. Guardia…·Cristiane Rodrigues Guzzo

The paper uses molecular dynamics simulations and SPR assays to analyze how SARS-CoV-2 variants bind to the ACE2 receptor and how this affects viral spread.

11 citations

humanprotein structure

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BioinformaticsBrazilian Journal of OncologyPeer-reviewedNov 20, 2020

Reboot: a straightforward approach to identify genes and splicing isoforms associated with cancer patient prognosis

Felipe R. C. dos Santos, Gabriela Der Agopian Guardia, Filipe Ferreira dos Santos, Pedro A. F. Galante

Reboot identifies genes and splicing isoforms linked to cancer patient prognosis using penalized Cox regression and bootstrap methods, validated on glioblastoma and pancreatic adenocarcinoma datasets.

19 citations

humanbulk RNA-seq

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