Author

Isaac Skromne

University of MiamiORCID 0000-0003-2369-7210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew J. DarriD· 1 shared Piyush Joshi· 1 shared Piyush K. JoshiiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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3 top collaborators · 1 mutual co-author link

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1 shared paperDevelopmental Biology

Andrew J. DarrORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintJul 18, 2020

A theoretical model of neural maturation in the developing spinal cord

Piyush Joshi, Isaac Skromne

The paper develops a theoretical model to study the spatiotemporal dynamics of signaling and transcription factor networks in spinal cord neural maturation.

DOI 10.1101/668640

statistical model

𝕏 PostBluesky

Developmental BiologyDevelopmental BiologyPeer-reviewedFeb 28, 2019

CDX4 regulates the progression of neural maturation in the spinal cord

Piyush K. Joshi, Andrew J. Darr, Isaac Skromne

The paper identifies CDX4 as a dual-function regulator in the spinal cord that controls the sequential loss of cell potency and acquisition of differentiation states during neural progenitor maturation.

14 citations

statistical modelgene regulatory network inference

𝕏 PostBluesky