Elizabeth A. Libby

A Multi-Tetracycline Responsive Induction System for Gene Expression in Bacillus subtilis

This paper develops a tetracycline-inducible gene expression system for Bacillus subtilis with high dynamic range and minimal leakiness across growth conditions.

Phosphorylation of a conserved intrinsically disordered region is necessary for activation of a bacterial Hanks-type Ser/Thr kinase signaling pathway

This study shows that phosphorylation of an intrinsically disordered region is essential for activating a bacterial kinase pathway, affecting antibiotic resistance and survival.

Protein sensors of bacterial kinase activity reveal antibiotic-dependent kinase activation in single cells

The paper develops new sensors to directly measure bacterial kinase activity at the single-cell level and shows that PrkC activity increases in response to a cell-wall-targeting antibiotic.