Alan Mao

TD2 is a new tool for ab initio annotation of protein-coding ORFs in transcripts, showing sensitivity and precision across diverse eukaryotic transcriptomes.

OpenSpliceAI improves SpliceAI by implementing it in PyTorch, enabling faster processing and retraining on non-human species with reduced memory usage.

LiftOn improves genome annotation by integrating DNA and protein alignments, enabling accurate annotation transfer between closely and distantly related species.

Splam improves spliced alignments by accurately predicting splice junctions in DNA, outperforming existing methods like SpliceAI across human and non-human species.