John F. Engelhardt

This study uses KRT7CreER ferrets to trace ductal epithelial lineage and pancreatic remodeling in health and cystic fibrosis.

This study identifies KRT7+ cells in airway glands as multipotent progenitors that support development, homeostasis, and regeneration, with potential implications for cystic fibrosis therapies.

This study identifies Lef1 as a key factor promoting ionocyte specification from submucosal gland progenitors, with Foxi1 playing a regulatory role in this process.

This study shows that a bleomycin-induced lung injury model in ferrets shares key pathophysiological, cellular, and molecular features with human idiopathic pulmonary fibrosis, suggesting its use for IPF research.