Ádám Póti

This study maps the mutational consequences of MMR gene deficiencies in cancer cells using CRISPR, mutation accumulation, and whole-genome sequencing, revealing multidimensional mutational phenotypes.

The paper defines the mutational profile of planarian regeneration and provides a de novo genome assembly for Schmidtea polychroa, finding a threefold increase in mutations during regeneration.

This study compares the mutagenicity of cisplatin, carboplatin, and oxaliplatin at equitoxic concentrations using whole genome sequencing and phenotypic assays, finding cisplatin induces more mutations and DNA damage.