scRGP: Prediction of Single-cell Genetic Perturbation Transcriptional Responses based on Rank in Multiple Scenarios
Yufeng Liu, Zhang Hao, Mingmin Xu, Duowei Wang, Weiwei Hu, Liangyun Zhang, Yong Yang, Cong Pian, Yuanyuan Chen
scRGP predicts single-cell genetic perturbation transcriptional responses using rank-based deep learning, improving performance over existing methods for single, double, and cross-cell-line perturbations.
bioRxiv · Sep 30, 2025 · PreprintBioinformatics