Evolutionary BiologyMolecular Systems BiologyPeer-reviewed
Genetic and selective constraints on the optimization of gene product diversity
Daohan Jiang, Nevraj S. Kejiou, Yi Qiu…·Matthew W. Pennell
The paper develops a mathematical model to predict isoform abundance distributions across species and genes, finding that factors beyond selection, like population size and cis-acting loci, significantly influence evolutionary outcomes.
3 citations