Author

Bo Zhu

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAORCID 0000-0003-2439-0026Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bo Zhu4 papers · Boston Children's Hospital

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:spatial transcriptomics· 2 Research Focus:trajectory inference· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:imaging· 1 Approach:large language model· 1

Frequent Co-Authors

Beibei HuangiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 23, 2026

Autonomous multimodal agents enable transparent, spatiotemporal reconstruction of immune dynamics in pancreatic cancer progression

Beibei Huang, Bo Zhu

The paper introduces an agentic computational framework to reconstruct immune dynamics in pancreatic cancer using H&E histology, identifying three temporally ordered immune-stromal states in mouse models.

DOI 10.64898/2026.04.20.719684

mousespatial transcriptomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 23, 2025

Architectural Fragmentation and Immune Reprogramming Define Early Malignant Transition in Lung Adenocarcinoma

Beibei Huang, Bo Zhu

This paper uses H&E slides and deep learning to reconstruct LUAD progression, identifying immune reprogramming and architectural fragmentation as key early malignant transitions.

DOI 10.1101/2025.10.23.684213

humanspatial transcriptomics

𝕏 PostBluesky