Author

Bo Zhu

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Arulsamy KulandaisamyiD· 1 shared Bandana SinghiD· 1 shared Da‐Zhi WangiD· 1 shared Douglas B. CowaniD· 1 shared Fachao Zhi· 1 shared Hong CheniD· 1 shared Hongying FaniD· 1 shared Jill Wylie‐SearsiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Arulsamy KulandaisamyORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Single-cell transcriptomics reveals chondrocyte state transitions and ECM remodeling in osteoarthritic knee cartilage

Bo Zhu, Xu Han, Yunqi Liang

The paper reanalyzes a public single-cell RNA sequencing dataset to identify chondrocyte state transitions and ECM remodeling in osteoarthritis, finding collagen network hubs as potential targets.

bioRxiv · Jun 29, 2026 · PreprintBioinformatics

Ybx1 Deficiency Causes ROS-Driven IBD-Like Intestinal Inflammation and Postnatal Lethality

Bo Zhu, Lakhansing Arun Pardeshi, Yingying Chen, Xianqing Zhou, Wei Ge

This study shows Ybx1 deficiency in zebrafish causes ROS-driven intestinal inflammation, MMP-mediated gut damage, and postnatal lethality, establishing a model for IBD-like disorders.

bioRxiv · Jan 28, 2026 · PreprintDevelopmental Biology

Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis

Qianman Peng, Arulsamy Kulandaisamy, Yao Wei Lu, Bo Zhu, Bandana Singh, Kui Cui, Jill Wylie‐Sears, Marina V. Malovichko, Scott Wong, Douglas B. Cowan, Masanori Aikawa, Sanjay Srivastava, Da‐Zhi Wang, Joyce E. Bischoff, Kaifu Chen, Hong Chen

This study shows that deleting CD45 in endothelial cells reduces atherosclerosis by inhibiting EndoMT and TGFβ signaling through increased FGFR2 and KLF2 expression.

bioRxiv · Sep 3, 2024 · PreprintCell Biology

Bacteroides fragilis defense against Cronobacter sakazakii -induced pathogenicity by regulating the intestinal epithelial barrier function and attenuating both apoptotic and pyroptotic cell death

Hongying Fan, Ruqin Lin, Zhenhui Chen, Xingyu Leng, Xianbo Wu, Yiduo Zhang, Bo Zhu, Qiwei Zhang, Yang Bai, Fachao Zhi

This study shows that B. fragilis ZY-312 protects against Cronobacter sakazakii-induced necrotizing enterocolitis by inhibiting invasion, epithelial barrier dysfunction, and dual cell death.

bioRxiv · Oct 12, 2018 · PreprintMicrobiology