GeneticsbioRxivPreprint
Generation of de novo miRNAs from template switching during DNA replication
Heli A. M. Mönttinen, Mikko J. Frilander, Ari Löytynoja
The paper shows that template-switching mutations generate over 6,000 hairpin structures in primates, leading to 18 new human miRNA genes, 26% of which emerged since primates originated.
DOI 10.1101/2023.04.19.537475