ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewed
Acquisition of an immunosuppressive microenvironment after CAR-T therapy drives T-cell dysfunction and resistance
Marianna Ponzo, Lorenzo Drufuca, Chiara Buracchi…·Chiara Francesca Magnani
This study shows that CAR-T therapy induces an immunosuppressive microenvironment, leading to T-cell dysfunction and resistance in B-ALL patients.