Author

Alessandro Rambaldi

Ospedale Papa Giovanni XXIIIORCID 0000-0002-3739-7502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberto MagiiD· 1 shared Alessandra MingrinoiD· 1 shared Alex MorettiiD· 1 shared Andrea BiondiiD· 1 shared Anna CandoniiD· 1 shared Benedetta RambaldiiD· 1 shared Chiara BuracchiiD· 1 shared Chiara CaprioliiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Alberto MagiORCID

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2 papers

Recent·Most cited

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedOct 1, 2025

Acquisition of an immunosuppressive microenvironment after CAR-T therapy drives T-cell dysfunction and resistance

Marianna Ponzo, Lorenzo Drufuca, Chiara Buracchi…·Chiara Francesca Magnani

This study shows that CAR-T therapy induces an immunosuppressive microenvironment, leading to T-cell dysfunction and resistance in B-ALL patients.

16 citationstop 3%

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GenomicsCommunications BiologyPeer-reviewedApr 8, 2023

High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.

Alberto Magi, Gianluca Mattei, Alessandra Mingrino…·Pier Giuseppe Pelicci

The paper uses nanopore sequencing to map DNA methylation in AMLs, revealing hypermethylation at CpG-poor regions drives chemoresistance through transcription factor networks.

13 citations

humanDNA methylation

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