BioinformaticsbioRxivPreprint
Rethinking scRNA-seq Trajectories in Phylogenetic Paradigms: Overcoming Challenges of Missing Ancestral Information
Julia Naas, Arndt von Haeseler, Christiane Elgert
CellREST reinterprets scRNA-seq trajectory reconstruction as a phylogenetic inference problem, uncovering circular processes and converging differentiation scenarios in simulated and experimental data.
DOI 10.1101/2025.07.22.664676