Author

Robert Wang

Children's Hospital of PhiladelphiaORCID 0000-0003-2614-5956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Alex KhodaverdianiD· 2 shared Nir YosefiD· 2 shared Alex LeeiD· 1 shared Ameya S. ChamphekariD· 1 shared Antoni RibasiD· 1 shared Beatrice D. ZhangiD· 1 shared Chenling A. XuiD· 1 shared Christopher S. SeetiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Alex KhodaverdianORCID

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3 papers

Recent·Most cited

BioinformaticsProceedings of the National Academy of SciencesPeer-reviewedMay 16, 2023

IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing

Yang Pan, John W. Phillips, Beatrice D. Zhang…·Yi Xing

IRIS identifies cancer immunotherapy targets from alternative splicing using transcriptomics data and validates them with patient T cells.

51 citationstop 2%

humanbulk RNA-seq

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BioinformaticsProceedings of the National Academy of SciencesPeer-reviewedMar 16, 2023

Theoretical Guarantees for Phylogeny Inference from Single-Cell Lineage Tracing

Robert Wang, Richard Zhang, Alex Khodaverdian, Nir Yosef

This paper develops two algorithms for exact phylogenetic reconstruction from CRISPR-Cas9 lineage tracing data and provides theoretical bounds on required recording sites.

18 citations

statistical modelphylogenetics / evolution

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BioinformaticsGenome biologyPeer-reviewedApr 14, 2020

Inference of Single-Cell Phylogenies from Lineage Tracing Data

Matthew G. Jones, Alex Khodaverdian, Jeffrey J. Quinn…·Nir Yosef

The paper introduces Cassiopeia, a method for inferring single-cell phylogenies from lineage tracing data, and benchmarks it against traditional methods using a large experimental dataset.

138 citationstop 3%

humanCRISPR screen

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