Daniel D. Sprockett

The paper compares gut microbiomes of Tsimane and Hadza populations to show that many microbes co-migrated with humans globally, but are now vanishing in industrialized populations.

This study shows that dietary transitions drive reproducible adaptive evolution in gut bacteria across multiple species, with specific genetic responses observed in key functions like invertases.

This study shows that gut bacterial symbionts of laboratory mice have accumulated genetic mutations faster than those of wild mice, likely due to genetic drift in captivity.

This study evaluates Hackflex library preparation for metagenomic sequencing, showing it recovers all members of a mock community and distinguishes microbiota between individual mice.

This study quantifies variability in host proteins and bacterial taxa in stool samples from healthy individuals, showing greater inter-subject variation than temporal or technical variation.