Maternal Trypanosoma cruzi infection is associated with significant placental remodeling regardless of vertical transmission
Sneider Alexander Gutierrez Guarnizo, Jaime So, Carolina Duque, Paloma Samame, Jean Karla Velarde, Emily Arteaga, Clariza Roxana, Luciana Basma, Liseth Roque, Beth J. Condori, Pepe M Obregón Maldonado, Edith Málaga, Jill M. C. Hakim, Shenice Harrison, Rony Pedro Colanzi, , The Chagas Disease Working Group in Bolivia and Peru
This study shows that maternal Trypanosoma cruzi infection causes significant placental remodeling and systemic changes, regardless of whether the infection is transmitted to the fetus, and identifies potential biomarkers for prenatal monitoring.
bioRxiv · Jan 13, 2026 · PreprintMolecular Biology