Author

Derek J. Essegian

University of MiamiORCID 0000-0003-2779-1992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Stephan C. SchüreriD· 2 shared Floritza Bustamante· 1 shared Jaime Rafael MerchaniD· 1 shared Rimpi KhuranaiD· 1 shared Valery A. Chavez-Perez· 1 shared Vasileios StathiasiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMolecular Biology

Stephan C. SchürerORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 9, 2022

Cellular And Molecular Effects Of Understudied Kinase Pregnancy Upregulated Non-Ubiquitous Calcium-Calmodulin Dependent Kinase (PNCK) In Renal Cell Carcinoma.

Derek J. Essegian, Valery A. Chavez-Perez, Floritza Bustamante…·Jaime Rafael Merchan

This study identifies PNCK as a differentially overexpressed kinase in RCC, showing its role in cell proliferation, apoptosis, and disease progression, suggesting it as a potential drug target.

DOI 10.1101/2022.05.09.491212

humanbulk RNA-seq

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BioinformaticsCell Reports MedicinePeer-reviewedOct 1, 2020

The Clinical Kinase Index: Prioritizing Understudied Kinases as Targets for the Treatment of Cancer

Derek J. Essegian, Rimpi Khurana, Vasileios Stathias, Stephan C. Schürer

The paper develops a scoring system to prioritize understudied kinases as potential cancer targets using TCGA data.

75 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky