The paper investigates tongue development anomalies in ciliopathies and shows that coordinated cellular processes are essential for normal development.

4 citations

mouseexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 6, 2020

Hedgehog signalling regulates patterning of the murine and human dentitions through Gas1 co-receptor function

Maisa Seppala, Béatrice Thivichon‐Prince, Guilherme Machado Xavier…·Martyn T. Cobourne

This study shows that Gas1 regulates tooth number and morphology in mice and humans by modulating Hedgehog and Wnt signaling during development.

DOI 10.1101/2020.11.06.371476

mousehuman

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJun 23, 2017

Sonic hedgehog is required for neural crest-dependent patterning of the intrinsic tongue musculature

Shigeru Okuhara, Anahid A. Birjandi, Hadeel Adel Al-Lami…·Sachiko Iseki

This study shows that Sonic hedgehog (Shh) is essential for patterning the intrinsic tongue muscles through cranial neural crest-derived mesenchyme in mice.

DOI 10.1101/154443

mouseexperimental assay

𝕏 PostBluesky