Siyuan Wu

This study benchmarks fusion detection methods using long-read RNA sequencing, finding that ONT PCR-cDNA with CTAT-LR-Fusion offers the best balance of precision and recall.

ICON improves cell type classification in scRNA-seq by incorporating isoform-level data, achieving better resolution than gene-level methods.

ScIsoX provides a framework to measure isoform-level transcriptomic complexity in single cells, revealing multidimensional patterns missed by gene-level approaches.