Author

Samuel WD Merriel

University of ManchesterORCID 0000-0003-2919-9087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Harry GreeniD· 2 shared Michael N. WeedoniD· 2 shared Sarah E. R. BaileyiD· 2 shared Amy P. WebsteriD· 1 shared Andrew R. WoodiD· 1 shared Anna MurrayiD· 1 shared Bethan Mallabar-RimmeriD· 1 shared Christina ThirlwelliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Harry GreenORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 18, 2026

Improved prostate cancer prediction by combining Prostate-Specific Antigen (PSA) test results with Genetic Risk Scores (GRS/PRS)

Jingzhan Lu, Ge Chen, Samuel WD Merriel…·Harry Green

The paper combines genetic risk scores with PSA test results and age to improve prostate cancer prediction, showing better performance than using either method alone.

DOI 10.64898/2026.05.14.26353195

humanstatistical model

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Genetic & Genomic MedicineEuropean Journal of Human GeneticsPeer-reviewedAug 1, 2024

Colorectal cancer risk stratification using a polygenic risk score in symptomatic patients presenting to primary care -- a UK Biobank retrospective cohort study

Bethan Mallabar-Rimmer, Samuel WD Merriel, Amy P. Webster…·Harry Green

This paper develops a polygenic risk score model to predict colorectal cancer risk in symptomatic patients using UK Biobank data, achieving high predictive accuracy.

6 citations

humanGWAS summary statistics

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