Author

Neeltje Steeghs

The Netherlands Cancer InstituteORCID 0000-0003-2989-2279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Martijn P. LolkemaiD· 2 shared Abel González-PéreziD· 1 shared Alexander GuseviD· 1 shared Amnon KoreniD· 1 shared Andrew Victor BiankiniD· 1 shared B BernsteiniD· 1 shared Carla van Herpen· 1 shared Charles L. SawyersiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Martijn P. LolkemaORCID

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2 papers

Recent·Most cited

GenomicsNature GeneticsPeer-reviewedNov 18, 2019

The mutational footprints of cancer therapies

Oriol Pich, Ferran Muiños, Martijn P. Lolkema…·Núria López-Bigas

This study identifies mutational footprints of six cancer therapies using whole-genome data from metastatic tumors to assess their contribution to mutation burden and risk of driver mutations.

309 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 11, 2019

Tumor mutational landscape is a record of the pre-malignant state

Kirsten Kübler, Rosa Karlić, Nicholas J. Haradhvala…·Gad A. Getz

The paper predicts cancer cell-of-origin from DNA sequences by matching mutational landscapes to chromatin modification patterns in normal tissues.

23 citations

humanwhole-genome sequencing

𝕏 PostBluesky