Joakim S. Dahlin

The paper develops a post-hoc method to link mutation status to single-cell transcriptomes using long-read sequencing, showing it can detect BCR::ABL1-positive cells in chronic myeloid leukemia.

The paper introduces an EPD assay to study human HSC lineage commitment and identifies IL-33 as a regulator of megakaryopoiesis by activating the MAPK pathway.

The paper uses single-cell RNA-sequencing and immunoprofiling to identify two transcriptionally distinct basophil populations in human peripheral blood.

This paper introduces PAGA, a method that reconciles clustering with trajectory inference by creating a topology-preserving graph map of single-cell data, demonstrating its effectiveness across multiple datasets.