A single-cell and multi-platform spatial atlas of the human pancreas resolves a transformation-associated epithelial axis and a recurrent boundary-organized tumour microenvironment
Kaili Liu, Hua Zhong, Rahhul S. Elangovan, Yuanhong Sun, Lin Wang, Abigael P. Williams, Trisha I. Valerio, Coline L. Furrer, Jacob P. Adams, Ashley R. Hoover, Wei R. Chen
This paper integrates single-cell and spatial data from multiple pancreas conditions to identify a transformation-associated epithelial axis and a recurrent tumour microenvironment organization.
bioRxiv · Aug 3, 2026 · PreprintCancer Biology