Hua Zhong

The paper develops a deep learning model from H&E images to predict T-effector biology and ICI response in ccRCC, showing strong correlation with RNA-based scores and clinical outcomes.

This paper integrates single-cell and spatial data from multiple pancreas conditions to identify a transformation-associated epithelial axis and a recurrent tumour microenvironment organization.

This study constructs a cross-model spatial and single-cell atlas of PKD, identifying Spp1 (osteopontin) as a conserved driver of disease progression through its signaling to Ly6clo monocytes.

The paper identifies ARID3a and CD68 as markers of activated naive B cell precursors in SLE, showing their association with autoimmunity and disease activity.

This study shows that hyperoxia impairs mitochondrial function and epithelial differentiation in neonatal airway cells through proteomic analysis and metabolic reprogramming.